The following link is to an article about DNA extracted from bones buried at Hopewell Mound Site. The results were compared to a database of mtDNA of groups from all over the world.
As more research is compiled and the database grows larger there is a definite possibility that may answer the question of who first populated the new world could be encoded in our DNA. I don’t want to sensationalize such findings as this is just the beginning of this type of research. However, keeping a mind open to all the possibilities and paying attention to the details may bring to light answers that were always staring right at us. There is a great contribution of all the sciences that may teach us to look at the whole picture and not just a piece that fits our preconceived notions.